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Read here, straight from the source's own words — every item keeps a link to the original. Newest first, always.
Thursday 11 December
Wednesday 10 December
Autonomous drone delivery in a Zip (Interview)
We're joined by Zipline cofounder / CTO, Keenan Wyrobek. Zipline is on a mission to build the world’s first logistics system that serves all people equally via their fleet of auton…
original ↗The AI engineer skills gap
Chris and Daniel talk with returning guest, Ramin Mohammadi, about how those seeking to get into AI Engineer/ Data Science jobs are expected to come in a mid level engineers (not e…
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Monday 8 December
Friday 5 December
Very important agents (Friends)
Nick Nisi joins us to dig into the latest trends from this year and how they're impacting his day-to-day coding and Vision Pro wearing. Anthropic's acquisition of Bun, the evolving…
original ↗Exploring Quantum Computing & Python Frameworks
What are the recent advances in the field of quantum computing and high-performance computing? And what Python tools can you use to develop programs that run on quantum computers? …
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Thursday 4 December
#750: re:Invent 2025 - Day 3 Wrapup
It is the end of re:Invent! Simon and Jillian share some updates and also take a moment to reflect on 2025.
original ↗Daniel Temkin and the Beauty of Esoteric Languages
What happens when code stops being useful and starts being art? Scott talks with artist and programmer Daniel Temkin about his new book Forty-Four Esolangs, a deep dive into the wo…
original ↗Werner Vogels predicts the future (Interview)
Amazon CTO, Werner Vogels, stops by to help us explore his tech predictions for 2026 and beyond. Will companionship be redefined by consumer robots? Will quantum-safe become the on…
original ↗#749: re:Invent 2025 - Swami Sivasubramanian Keynote
Simon and Jillian catch you up on the highlights from today's keynote PLUS all the "pre:Invent" announcements that took place prior to the event!
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Wednesday 3 December
Being a founding engineer at an AI startup
Brought to You By:• Statsig — The unified platform for flags, analytics, experiments, and more. • Linear — The system for modern product development. —Michelle Lim joined…
original ↗#529: Computer Science from Scratch
See the full show notes for this episode on the website at talkpython.fm/529
original ↗#748: re:Invent 2025 - Matt Garman Keynote
In this episode, Matt Garman's 2025 re:Invent keynote unveils exciting AI advancements, including Amazon Nova to Lite, a cost-effective reasoning model, and Amazon Nova 2 Sonic, a …
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Tuesday 2 December
Technical advances in document understanding
Chris and Daniel unpack how AI-driven document processing has rapidly evolved well beyond traditional OCR with many technical advances that fly under the radar. They explore the pr…
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Story: The Bug He Couldn't Name - A 15-Year Fight Inside One Developer's Mind
Imagine facing a problem you can't name, something that feels bigger than any bug you've ever had to fix. How do you debug your own mind when you don't even know what's wrong? Burk…
166: Maxie
Maxie Reynolds loves an adventure, especially the kind where she’s breaking into buildings (legally). In this episode, she shares stories from her time as a professional penetratio…
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Monday 1 December
Sunday 30 November
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#486 – Michael Levin: Hidden Reality of Alien Intelligence & Biological Life
Michael Levin is a biologist at Tufts University working on novel ways to understand and control complex pattern formation in biological systems. Thank you for listening ❤ Check ou…
#528: Python apps with LLM building blocks
See the full show notes for this episode on the website at talkpython.fm/528
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Friday 28 November
Thursday 27 November
The Digital Runway: IT at the Philadelphia Airport with Camille Tomlin
Scott sits down with Camille Tomlin, Head of IT at Philadelphia International Airport, to explore the intersection of aviation, technology, and leadership. They discuss how airport…
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We still need to talk about vibe coding: Reflections on 2025's word of the year
Vibe coding was, remarkably, named word of the year by the Collins English Dictionary at the start of November 2025 — pretty good going for a term that was only coined in February.…
Wednesday 26 November
Chris on AI, autonomous swarming, home automation and Rust!
This episode is a special crossover between the Practical AI podcast and The Changelog podcast. Chris was recently invited by longtime friends Jerod Santo and Adam Stacoviak, cohos…
original ↗Code security for software engineers
Brought to You By:• Statsig — The unified platform for flags, analytics, experiments, and more. Statsig are helping make the first-ever Pragmatic Summit a reality. Join me and…
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Monday 24 November
Friday 21 November
Thursday 20 November
Wednesday 19 November
Beyond note-taking with Fireflies
Fireflies CEO, Krish Ramineni shares how the company is transforming AI-powered note-taking into a deeper layer of knowledge automation. He breaks down the technology behind real-t…
original ↗How AI will change software engineering – with Martin Fowler
Brought to You By:• Statsig — The unified platform for flags, analytics, experiments, and more. AI-accelerated development isn’t just about shipping faster: it’s about measuri…
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